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肝细胞核因子4α及1α与糖尿病的关系

彭姝彬,沈俊,程孟荣,黄青阳

CHINESE JOURNAL OF DIABETES（2007）

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Abstract
肝细胞核因子(HNF)是一类异质的保守转录因子,参与调节肝脏内糖代谢、脂代谢相关基因的表达.HNF在胰岛中也有表达,其家族成员在β细胞胰岛素基因的转录活化、维持胰岛β细胞正常功能及调节糖代谢等方面都起重要的作用.
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