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颈动脉粥样硬化斑块成分与性别的相关性研究

Chinese Journal of Geriatric Heart Brain and Vessel Diseases(2014)

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Abstract
目的 探讨颈动脉粥样硬化患者斑块成分的性别差异.方法 选取进行颈动脉3.0T MR高分辨扫描的颈动脉粥样硬化斑块患者154例,男性95例,女性59例,根据MR扫描结果,对斑块成分和性质进行分析,比较男、女性的斑决成分差异.结果 男性斑块内富脂质坏死核(42.1% vs 20.0%,P=0.005)和薄或破裂纤维帽(59.7% vs 39.5%,P=0.046)的发生率明显高于女性;女性斑块内钙化的发生率有高于男性的趋势(74.6% vs 65.3%,P=0.225),男性与女性斑块内出血发生率比较,差异无统计学意义(24.2% vs 22.0%,P=0.756).结论 颈动脉粥样硬化斑块患者中,男性不稳定斑块的发生率高于女性,这可能有助于解释脑卒中发病率的性别差异.
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Key words
carotid stenosis,atherosclerosis,magnetic resonance imaging,sex factors
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