抗黑色素瘤分化相关基因-5(MDA5)抗体与抗MDA5抗体阳性皮肌炎

Chinese Journal of Internal Medicine(2018)

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Abstract
抗黑色素瘤分化相关基因-5melanoma differentiation-associated gene 5,MDA5)抗体是近年来发现的一种肌炎特异性抗体,多见于皮肌炎(DM)患者.间质性肺疾病(ILD)是DM常见的肺部表现,近几年的研究表明血清抗MDA5抗体与DM相关ILD密切相关.为提高对抗MDA5抗体阳性DM患者的认识与诊治水平,现对该病相关诊治进展综述如下.
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