拉米夫定治疗慢性乙型肝炎对血清肝纤维化指标影响的临床观察
JOURNAL OF CLINICAL HEPATOLOGY（2006）
Abstract
目的探讨拉米夫定治疗慢性乙型肝炎对患者血清肝纤维化指标的影响.方法对42例慢性乙型肝炎患者在拉米夫定治疗前和治疗1年后测定血清透明质酸(HA)、层粘蛋白(LN)、Ⅲ型前胶原(PCⅢ)和Ⅳ型胶原(ⅣC)水平,并与39例对照组进行比较.结果治疗组治疗后4项血清肝纤维化指标明显下降(P均＜0.01);治疗后治疗组与对照组相比也有显著性差异(P均＜0.01).结论拉米夫定治疗慢性乙型肝炎对血清肝纤维化指标有明显降低作用.
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Key words
hepatic fibrosis index,hepatitis,serum,lamivudine-treated
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