脓毒症心肌损伤机制研究进展

Journal of Internal Intensive Medicine(2018)

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Abstract
脓毒症是一种由微生物感染引起,导致宿主调节功能异常,包括炎性因子级联释放,内皮功能障碍,细胞凋亡,免疫抑制,最终导致多器官功能障碍的疾病综合征[1].其对心肌的损伤程度是患者预后的关键.据流行病学调查研究,约40%的脓毒症患者出现心肌损伤,有心肌损伤的患者病死率明显增高[2].
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