肾性尿崩症治疗研究进展
Chinese Journal of Practical Internal Medicine（2016）
Abstract
肾性尿崩症(NDI)是由于肾脏对精氨酸加压素(AVP)部分或完全抵抗造成的尿液浓缩障碍性疾病,主要分为先天性和获得性两大类.先天性NDI由AVPR2或AQP2基因突变引起,也可以是遗传病的继发改变,如Bartter综合征等[1].获得性NDI比先天性NDI更为常见,可由药物、电解质紊乱和肾脏梗阻性疾病等引起[2].
MoreKey words
diabetes insipidus,nephrogenic,AVPR2,aquaporin 2
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