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IL-33/ST2信号通路与炎症性肠病的关系

Yuemei DONG,Fang ZHANG,Meihua ZHAO,Na MA,Baisui FENG

Chinese Journal of Gastroenterology（2019）

Cited 1|Views7
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Abstract
白细胞介素-33(IL-33)是新发现的IL-1超家族细胞因子,通过其受体ST2介导的通路参与多种免疫相关疾病的发生、发展,包括炎症性肠病(IBD),但其作用机制尚未明确.有研究显示IL-33在肠黏膜中可能发挥促炎和保护的双重作用.本文就IL-33/ST2信号通路与IBD的关系作一综述.
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