参麦养阴化瘀汤对慢性萎缩性胃炎临床疗效及对血清炎性因子的影响
Chinese Journal of Integrated Traditional and Western Medicine on Digestion(2017)
Abstract
[目的]观察参麦养阴化瘀汤对阴虚血瘀型萎缩性胃炎的临床疗效及对血清炎性因子的影响.[方法]58例符合诊断及纳入标准的萎缩性胃炎患者,随机分为对照组(29例)和治疗组(29例),其中对照组给予维酶素片口服治疗,治疗组给予参麦养阴化瘀汤治疗,2组疗程均为8周,分别观察2组患者临床症状、胃黏膜病理改变及血清炎性因子(IL-6、IL-1β、NOS2)水平.[结果]治疗组总有效率为93.1%,治疗组明显优于对照组(P<0.05);治疗组治疗后胃黏膜组织黏膜炎症、活动度、腺体萎缩、肠上皮化生及异型增生较本组治疗前显著改善(P<0.01),且治疗组明显优于对照组(P<0.01);治疗组治疗后血清IL-6、IL-1、NOS2水平与本组治疗前比较均明显降低(P<0.01),2组治疗后组间比较,治疗组明显优于对照组(P<0.01).[结论]参麦养阴化瘀汤能够显著改善阴虚血瘀型萎缩性胃炎临床症状及胃黏膜组织病理学情况,降低血清炎性因子的水平,临床疗效显著.
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Key words
Shenmai Yangyin Huayu Decoction,atrophic gastritis,clinical effect,inflammatory factor
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