局灶节段硬化性肾小球肾炎的中西医结合治疗研究进展
Chinese Journal of Integrated Traditional and Western Nephrology（2019）
Abstract
局灶节段硬化性肾小球肾炎( focalsegmental glomerular sclerosis,FSGS)是一组病理诊断学名词,其病理表现为局灶性( <50％的肾小球受累)、节段性(非累及整个肾小球)肾小球硬化性病变,常伴不同程度的小管间质损害. 免疫荧光显示IgM及C3 呈团块样沉积在肾小球病变区,电镜可见足突广泛融合. 根据其硬化部位及细胞增殖特点的不同,可分为非特殊型、门周型、顶端型、塌陷型、细胞型5个亚型. 临床上以非特殊型最多见,约占半数以上[1].
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