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Lp-PLA2及hsCRP对于无症状颈动脉粥样硬化患者疗效的评估价值

Cardiovascular Disease Journal of Integrated Traditional Chinese and Western Medicine(Electronic)(2018)

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Abstract
目的 观察颈动脉斑块不稳定患者治疗前后血浆hsCRP及Lp-PLA2浓度变化,初步探讨两者对于无症状颈动脉粥样硬化患者疗效的评价.方法 选取我院无症状颈动脉不稳定斑块患者60例,随机分为两组,试验组予干预前及后3月、6月、12月斑块趋于稳定,血浆hsCRP浓度分别为3.52±2.12 ug/mL,2.52±1.99 ug/mL,1.98±1.56 ug/mL,1.5±0.78 ug/mL,血浆Lp-PLA2浓度分别为58.43±40.01 ug/L,33.93±23.12 ug/L,25.38±10.66 ug/L,16.78±9.56 ug/L,两者均下降显著,差异有统计学意义(P<0.05),对照组前后无明显变化;差异无统计学意义(P>0.05).结论 Lp-PLA2及hsCRP有助于客观、有效的评估无症状颈动脉粥样硬化患者疗效.
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