泛素调控蛋白A20与消化疾病关系的研究进展

Chinese Journal of Gastrointestinal Endoscopy (Electronic Edition)(2017)

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Abstract
新型泛素(Ubiquitin)调控蛋白A20又被称为TNFAIP3,在机体免疫调控、胃肠机能和肿瘤发生等领域发挥了多方面的功能.本文将结合其与消化疾病关系,探讨对胃肠黏膜屏障胃肠黏膜免疫的调控,及其表达缺失造成胃肠黏膜破坏胃肠免疫紊乱和菌群失调的作用机制.
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