LI-cadherin与肝细胞癌关系的研究进展
International Journal of Surgery(2014)
Abstract
LI-cadherin是新近发现的钙黏蛋白超家族的成员之一,肝肠钙黏蛋白是依赖Ga2+的介导细胞与细胞之间黏附作用的跨膜糖蛋白,参与细胞、组织器官和机体机能的维持.LI-cadherin在肝细胞癌的发生、发展中发挥着重要作用,LI-cadherin在肝细胞癌中的高表达导致细胞间黏附作用降低,引起肝细胞癌转移.
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Key words
Li-cadherin,Liver neoplasms,Tumorigenesis,Prognosis,Neoplasm metastasis
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