神经源性异位骨化发病机制的研究进展
Chinese Journal of Trauma(2020)
Abstract
神经源性异位骨化(NHO)是在软组织中出现新生骨组织的现象,与中枢神经损伤相关,可引起肢体活动障碍、剧烈疼痛和皮肤溃疡等严重并发症,其发病机制尚不明确。近年针对NHO的发病机制有了更深入的研究,并据此提出了新的监测和治疗靶点。笔者从促进成骨诱导因素、成骨前体细胞、成骨微环境三个方面对NHO的发病机制进行综述,为临床诊疗提供依据。
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Key words
Ossification, heterotopic,Bone morphogenetic proteins,Mesenchymal stem cells
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