P120连环蛋白/转录抑制因子Kaiso与Wnt信号通路在肿瘤发病机制中的作用

Chinese Journal of Operative Procedures of General Surgery(Electronic Version)(2017)

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Abstract
异常的经典的Wnt信号通路的激活可以促进肿瘤的发生.P120连环蛋白/转录抑制因子Kaiso对Wnt信号通路的靶基因具有调控作用,影响Wnt信号通路的活动,从而影响肿瘤发生的过程.
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Key words
Neoplasms,Signal transduction,Catenins,Transcription factors
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