甲状旁腺激素与认知功能
Chinese Journal of Nephrology, Dialysis & Transplantation（2019）
Abstract
原发和继发性甲状旁腺功能亢进患者中均有甲状旁腺激素(PTH)升高与认知功能受损有关的报道,甲状旁腺切除手术能明显改善甲状旁腺功能亢进患者的认知障碍.PTH造成认知功能受损的机制不明,可能是通过与脑内的PTH受体结合,调节钙浓度,造成细胞内钙超载;或者发挥血管活性作用,影响脑血流,从而引起认知障碍.
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