ALA-PDT联合0.1%他克莫司软膏治疗玫瑰痤疮疗效观察与分析
wf(2016)
Abstract
目的:观察ALA-PDT(5-氨基酮戊酸光动力疗法)联合0.1%他克莫司软膏治疗玫瑰痤疮的疗效及安全性。方法:将95例Ⅰ型及Ⅱ型玫瑰痤疮患者随机分为治疗组、对照1组及对照2组。治疗组及对照1组采用双波长ALA-PDT治疗,每周1次,共治疗4次,同时,治疗组及对照2组采用0.1%他克莫司软膏,每日2次,连续8周。结果:治疗第8周后,治疗组、对照1组及对照2组总有效率分别为86.11%、62.96%及34.38%,均未见严重不良反应,治疗组与两对照组比较,总有效率差异有统计学意义(P<0.05)。结论:ALA-PDT联合0.1%他克莫司软膏治疗玫瑰痤疮安全、有效,可明显改善患者生活质量,且不良反应少。
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Key words
5-aminolevulinic acid-photodynamic therapy,tacrolimus,rosacea,combined,observation of therapeutic effect
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