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拓扑异构酶Ⅱα在前列腺癌中的研究进展

Journal of Clinical Urology(2019)

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Abstract
拓扑异构酶Ⅱα(TOP2α)是控制DNA拓扑状态和细胞增殖的一类酶蛋白.它可能成为一种新型前列腺癌(PCa)的标记物,同时可以较好地评估PCa患者的预后.将有助于预测PCa预后、评估疗效及降低医疗成本.本文将对该标记物的特点及临床应用作一综述.
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