他克莫司对阿霉素肾病大鼠肾脏的保护作用及机制研究

Chinese Journal of Nephrology(2017)

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Abstract
蛋白尿是肾脏疾病最常见的临床表现,也是肾病综合征的诊断标准之一.蛋白尿的形成主要与肾小球滤过屏障受损、肾小管重吸收障碍、肾和尿路排泌有关.肾小球足细胞及足突之间的裂隙膜是最后一道滤过屏障, Nephrin分子为其重要的结构基础.
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