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2018年ASCO年会CDK4/6抑制剂联合内分泌治疗晚期乳腺癌最新进展解读

Tianhong Li,Fang Guo,Xiaodong Xie

Journal of Endocrine Surgery（2019）

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Abstract
内分泌治疗是激素受体阳性晚期乳腺癌的主要治疗手段,如何逆转内分泌耐药及内分泌治疗新药成为肿瘤界关注的焦点.细胞周期依赖激酶(cyclin dependent kinase,CDKs)研究发展迅速,选择性CDK4/6抑制剂可明显延长乳腺癌内分泌耐药,改善患者的无进展生存期.目前已被批准用于晚期乳腺癌的标准治疗.
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Key words
Advanced breast cancer,Endocrine therapy,American Society of Clinical Oncology(ASCO)
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