抗N-甲基-D-天门冬氨酸受体脑炎研究进展

Chinese Journal of Applied Clinical Pediatrics(2016)

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Abstract
抗N-甲基-D-天门冬氨酸受体(NMDAR)脑炎是一种以显著的行为异常及精神症状为临床表现的亚急性自身免疫性脑炎,由抗体作用于NMDAR的NR1或NR2亚基所致.本病并非少见,及早诊断及早期免疫治疗能改善预后及减少复发.现就抗NMDAR脑炎流行病学、发病机制、临床表现、诊断、治疗及预后进行综述,以提高临床医师对本病的认识.
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Key words
Anti-N-methyl-D-aspartate receptor encephalitis,Disinhibited behaviour,Psychiatric symptoms,Immunotherapy,Remove teratomas
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