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缺氧缺血性脑病新生大鼠脑内单胺类神经递质的改变

程秀永,栾斌,李俊才,王来栓,朱长连,屈志炜, 刘云

JOURNAL OF APPLIED CLINICAL PEDIATRICS（2001）

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Abstract
目的研究新生儿缺氧缺血性脑病(HIE)的发病机制。方法制作新生大鼠HIE模型，用高效液相电化学法检测脑组织单胺类神经递质含量。结果 HIE组结扎侧单胺类神经递质含量明显增加，与结扎对侧及正常对照组相比有显著性差异(P＜0.01)。结论单胺类神经递质参与了HIE的病理生理过程。
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Key words
monoamine neurotransmitters,hypoxicischemic encephalopathy,newborn rat brain tissue
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