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先天性肾积水相关基因的动物研究新进展

CHINESE JOURNAL OF PEDIATRIC SURGERY(2009)

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Abstract
先天性肾积水是小儿外科常见疾病之一,但先天性.肾积水的发病机制和遗传学特征尚未完全明确.近年来,国外对先天性肾积水的病因研究多集中在基因水平,通过基因敲除或基因沉默等技术创建出肾积水的动物突变体模型,对先天性肾积水的发病有了更深入的认识,现综述如下.
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