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局灶节段性肾小球硬化的流行病学进展

Journal of Clinical Pediatrics(2018)

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Abstract
局灶节段性肾小球硬化(FSGS)是一种临床病理综合征,病理以局灶节段分布的肾小球硬化及足细胞的足突融合为特征;临床主要表现为大量蛋白尿和肾病综合征;多表现为激素耐药,且常进展成终末期肾病;是儿童时期进展为终末期肾病的主要疾病之一.近年来全球报道FSGS肾活检检出率呈增多趋势,文章综述FSGS的流行病学进展.
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