胆囊炎与胆囊壁肥厚型腺癌的关系
CHINESE JOURNAL OF CLINICAL ONCOLOGY(2004)
Abstract
大量的临床材料发现长期的慢性胆囊炎,引起胆囊壁的局限性或弥漫性增厚,粘膜上皮增生,异型或上皮脱失,罗阿氏窦下延(变深),深达肌层或穿过肌层并伴有上皮异型增生[1~3].本文通过研究慢性胆囊炎后不同肥厚程度的胆囊壁组织中多种癌基因相关蛋白的表达与胆囊腺上皮增生、不典型增生及胆囊壁肥厚型癌变间的关系,认识到慢性胆囊炎胆囊壁肥厚与慢性胆囊炎后胆囊壁肥厚型腺癌密切相关.
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