Addressing viral resistance through vaccines.

FUTURE VIROLOGY(2015)

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摘要
Antimicrobial resistance is a serious healthcare concern affecting millions of people around the world. Antiviral resistance has been viewed as a lesser threat than antibiotic resistance, but it is important to consider approaches to address this growing issue. While vaccination is a logical strategy, and has been shown to be successful many times over, next generation viral vaccines with a specific goal of curbing antiviral resistance will need to clear several hurdles including vaccine design, evaluation and implementation. This article suggests that a new model of vaccination may need to be considered: rather than focusing on public health, this model would primarily target sectors of the population who are at high risk for complications from certain infections.
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关键词
antimicrobial resistance,antiviral resistance,cytomegalovirus,hepatitis C,HIV,influenza,vaccines,vaccine design,vaccine evaluation,vaccine implementation
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