mTOR与胃癌
Journal of International Oncology（2012）
Abstract
哺乳动物雷帕霉素靶蛋白(mTOR)是一种非典型的丝氨酸/苏氨酸蛋白激酶,属于磷脂酰肌醇激酶相关激酶( PIKK)蛋白家族成员.mTOR在肿瘤细胞生长、凋亡和肿瘤血管生成方面起着重要作用.目前以mTOR为靶点的分子靶向药物治疗已成为当前研究的热点.
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Key words
Mammals,Protein kinase inhibitors,Stomach neoplasms
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