视神经脊髓炎谱系疾病的免疫治疗策略
Chinese Journal of Neurology(2017)
Abstract
视神经脊髓炎谱系疾病(neuromyelitis optica spectrum disorders, NMOSD)是一类中枢神经系统(central nervous system, CNS)自身免疫性疾病,以反复发作的视神经炎和长节段横贯性脊髓炎为主要临床特征.2004年,水通道蛋白4(aquaporin 4, AQP4)抗体的发现使得NMOSD有别于多发性硬化(multiple sclerosis, MS)而成为一个独立的疾病实体.
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