缬沙坦对大鼠局灶性脑缺血保护作用的实验研究
CHINESE JOURNAL OF NEUROLOGY(2003)
Abstract
缬沙坦(valsartan)是一种新型的血管紧张素Ⅱ(AngⅡ)受体1拮抗剂 (AAG).资料表明,长期应用AAG 能够降低高血压患者脑卒中的发生率.为探讨AAG是否对缺血性脑损伤有保护作用,我们取正常血压大鼠,采用大脑中动脉闭塞(MCAO)模型,观察缬沙坦对大鼠脑缺血的保护作用.
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