神经性厌食患者血浆催产素水平及临床特征的研究

Jing-jie ZHANG,Jue CHEN,Qing KANG,Zhi-guang LIN,Jia-bin HUANG,Qing FAN,Qiang LIU,Shun-ying YU,Ming-dao ZHANG

Journal of Clinical Psychiatry（2017）

Cited 2|Views19

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Abstract

目的:探讨神经性厌食症(AN)患者与正常对照者血浆催产素(0T)水平及AN不同亚型临床特征的差异. 方法:采用酶联免疫法,分别测定41例AN患者和44例正常对照者的血浆OT含量.结果:AN患者血浆OT水平低于正常对照组[(86.54±32.45) pg/ml,(121.19±83.05) pg/ml;t=-2.499,P=0.014],差异具有统计学意义;AN限制型与暴食/清除型患者OT水平比较[(90.63±35.49) pg/ml;(83.00±29.96) pg/ml,t=0.747,P=0.459],差异无统计学意义. 结论:AN患者OT水平较正常对照降低,支持AN患者存在OT水平低下的假说;并提示AN两亚型有着相同的OT病理机制.

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Key words

anorexia nervosa,oxytocin,eating disorder,subtype

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