髓鞘少突胶质细胞糖蛋白抗体与儿童获得性脱髓鞘综合征
Journal of Brain and Nervous Diseases（2020）
Abstract
髓鞘少突胶质细胞糖蛋白抗体(myelin oligodendrocyte glycoprotein antibodies,MOG-Abs)相关炎性脱髓鞘疾病是一种与MOG自身抗体相关,有其独特的临床特征及MRI表现,不同于多发性硬化(multiple sclerosis ,MS)和视神经脊髓炎谱系疾病(neuromyelitis optica spectrum disorders ,NMOSD)的独立疾病实体.最初,O'connor等 [1]应用四聚体放射免疫检法,在儿童急性播散性脑脊髓炎(acute disseminated encephalomyelitis ,ADEM)患者中首先检测到了MOG抗体.
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