MPO-ANCA阳性肥厚性硬脑膜炎1例合并文献复习
Journal of Apoplexy and Nervous Diseases（2018）
Abstract
肥厚性硬脑膜炎( hypertrophic cranial pachymeningitis , HCP)是一种以颅内硬脑膜局限或弥漫性增厚及纤维化为表现的慢性炎性病变[1] ,临床表现无特异性,主要为慢性头痛、多组脑神经损害、共济失调及癫痫发作,核磁可见大脑镰及小脑幕脑膜局限或弥漫性增厚,并有明显强化. 病因可分为继发性硬脑膜炎及特发性硬脑膜炎,继发性硬脑膜炎病因多种,主要为感染、肿瘤、自身免疫性疾病等因素;特发性硬脑膜炎(idiopathic hypertrophic pachymeningitis ,IHP)无明确病因,为排除性诊断,可经病理证实的慢性纤维增生性病变.现分享我院收治的MPO-ANCA阳性肥厚性硬脑膜炎1例,并复习相关文献,以提高临床医生对此疾病的认识.
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