髓样细胞触发受体样转录因子-1与急性脑梗死的相关研究
Journal of Apoplexy and Nervous Diseases(2017)
Abstract
目的 通过检测血小板表面髓样细胞触发受体样转录因子-1(Triggering receptor expressed on myeloid cells-like transcript 1,TLT-1)在急性脑梗死(acute cerebral infarction,ACI)患者的表达水平,探讨其与急性脑梗死的关系.方法 采用流式细胞术(flow cytometry,FCM)检测脑梗死组与对照组髓样细胞触发受体样转录因子-1的表达水平,并进行相关分析.结果 脑梗死组髓样细胞触发受体样转录因子-1的表达水平明显高于对照组(P<0.01);且与脑梗死的病情严重程度和病灶大小呈正相关(r=0.656,P<0.01;r=0.593,P<0.01).Logistic回归分析显示髓样细胞触发受体样转录因子-1是急性脑梗死发病的独立危险因素(OR值=1.155,95%CI 1.105~1.207,P<0.01).结论 髓样细胞触发受体样转录因子-1可能是预测脑梗死的发病风险、评估病情严重程度和预后的生物指标.
MoreTranslated text
Key words
Cerebral infarction,Triggering receptor expressed on myeloid cells-like transcript 1 (TLT-1),Incidence risk,Severity
AI Read Science
Must-Reading Tree
Example
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined