注射用干扰素致重症药疹12例临床分析
Journal of Diagnosis and Therapy on Dermato-venereology(2014)
Abstract
目的:探讨注射用干扰素在治疗病毒性肝炎过程中导致重症药疹的临床特征以及治疗体会.方法:收集我院皮下注射干扰素治疗病毒性肝炎导致重症药疹的12例患者的临床资料,分析其病史、临床特点、治疗情况以及预后.结果:注射用干扰素所致重症药疹以重症多形红斑型为主,共9例,占75%,中毒性表皮坏死松解型药疹2例(16.7%),剥脱性皮炎型药疹1例(8.3%).12例患者在停用干扰素并系统应用糖皮质激素和人免疫球蛋白等治疗后全部痊愈出院.结论:注射用干扰素可导致重症药疹,应及时停用干扰素,应用糖皮质激素和人免疫球蛋白等治疗可取得较好效果.
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