寻常型银屑病患者血清HPA和VEGF水平检测及与PASI评分的相关性分析
Chinese Journal of Dermatovenerology of Integrated Traditional and Western Medicine（2018）
Abstract
目的 检测寻常型银屑病患者血清肝素酶(HPA)和血管内皮生长因子(VEGF)水平并探讨其临床意义.方法 采用酶联免疫吸附法(ELISA)检测90例寻常型银屑病患者血清HPA和VEGF水平,并以60名正常人作对照.结果 寻常型银屑病患者血清HPA和VEGF水平均显著高于对照组(P,＜0.05);进行期患者血清HPA和VEGF水平均显著高于静止期患者(P＜0.05);血清HPA和VEGF水平均与银屑病皮损面积及严重程度指数(PASI)评分呈正相关(P＜0.05).结论 寻常型银屑病患者血清中HPA和VEGF水平显著升高,与疾病活动和严重程度密切相关,有助于对银屑病病情的判断.
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