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糖尿病足发病机制的研究进展

China journal of Leprosy and Skin Diseases(2015)

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Abstract
糖尿病足是糖尿病的严重并发症,发病机理较为复杂,可能与遗传、神经病变、血管病变、外部压力和感染等相关。在糖尿病足的发生和发展过程中,遗传因素、神经病变和血管病变相互作用,导致体内代谢失调、神经功能紊乱、血液供应和循环障碍。当足部压力异常改变时,引起感染几率增加,进而发生下肢溃疡、坏疽等。
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Key words
diabetic foot,pathogenesis,genetics,neuropathy,vasculopathy
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