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吉非替尼引起丘疹脓疱样疹3例

The Chinese Journal of Dermatovenereology(2020)

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Abstract
1临床资料 例1女,51岁,头皮红斑、丘疹、脓疱伴瘙痒及脱发5个月,加重1周.患者半年前在外院确诊为非小细胞肺癌脑部转移,予口服人类表皮生长因子受体抑制剂吉非替尼(Gefitinib),250 mg/d治疗.用药20 d后,枕部出现大小不一的红斑,其上散在针尖大小的丘疹及脓疱,伴瘙痒,后逐渐增多加重,红斑融合成片伴脱发及黄色渗液,瘙痒明显.
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