ALA-PDT联合氩离子束凝固术治疗肛周巨大尖锐湿疣45例临床观察
The Chinese Journal of Dermatovenereology(2017)
Abstract
目的 评价5-氨基酮戊酸光动力疗法(5-aminolevulinic acid-photodynamic therapy,ALA-PDT)联合氩离子束凝固术(argon plasma coagulation,APC)治疗肛周巨大尖锐湿疣(giant condyloma acuminata,GCA)的临床疗效及安全性.方法 将入选的90例肛周GCA患者采用简单随机方法分为治疗组及对照组,每组45例,全部患者予APC去除可见疣体,1周后治疗组患者(45例)采用ALA-PDT治疗,1次/周,连续3周.治疗结束后两组患者均随访6个月.结果 随访结束时,治疗组临床痊愈41例,复发4例,复发率9.76%;对照组临床痊愈34例,复发11例,复发率32.35%,两组复发率比较:差异有统计学意义(P均<0.05),即治疗组的临床疗效明显优于对照组.结论 ALA-PDT联合APC治疗肛周GCA疗效确切,治愈率高,复发率低.
MoreKey words
5-aminolevulinic acid-photodynamic therapy,Giant condylomata acuminata,Perianal,Argon plasma coagulation
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