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雷公藤多甙联合低分子肝素/氯吡格雷治疗青斑样血管病10例

Ang-yuan SUN,Yue-yang LIU,Tie-nan LI,Chun-lin JIN,Qiang WANG,Xiao-jie SUN,Qing-yan CHEN

The Chinese Journal of Dermatovenereology（2016）

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Abstract
目的 评价雷公藤多甙片(GTT)联合低分子肝素针(LMWH)/氯吡格雷片治疗青斑样血管病(LV)的临床疗效和安全性.方法 对常规治疗效无效的10例LV患者,予GTT片联合LMWH/氯吡格雷片治疗(强化期:GTT片20mg口服,2～3次/d,低分子肝素0.3mL皮下注射,1次/d.维持期:GTT片10mg口服,2～3次/d,氯吡格雷75mg口服,隔日1次).随访3个月～1年.结果 强化治疗2周后,6例溃疡开始愈合,疼痛消失;治疗6周后,8例溃疡愈合.疗程中均不良反应少且轻微.结论 雷公藤多甙片联合低分子肝素针/氯吡格雷片对于常规治疗疗效差的青斑样血管病安全有效.
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Key words
Glucosidorum tripterygll totorum,Low molecular weight heparin injection,Clopidogrel,Livedoid vasculopathy
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