持续正压通气治疗对重度OSAHS患者听功能的影响
Journal of Audiology and Speech Pathology(2018)
Abstract
目的 探讨重度阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea hypopnea syndrome,OS-AHS)患者的听功能特征及持续气道正压通气(continuous positive airway pressure,CPAP)治疗对其听觉的影响.方法 对12例重度OSAHS患者(OSAHS组)CPAP治疗前后、12例单纯打鼾者(单纯鼾症组)、12例正常人(正常对照组)行纯音测听、畸变产物耳声发射(distortion product otoacoustic emissions,DPOAE)及听性脑干反应(auditory brainstem responses,ABR)测试,比较其结果.结果 OSAHS组8000Hz处纯音听阈提高,各频率DPOAE反应幅值不同程度下降,检出率明显降低,ABR波Ⅰ、Ⅲ、Ⅴ潜伏期及Ⅲ-Ⅴ波间期、Ⅰ-Ⅴ波间期均延长,与其它两组相比较差异有统计学意义(P<0.05);而其余频率纯音听阈、ABRⅠ-Ⅲ波间期及波Ⅴ反应阈差异无统计学意义(P>0.05).OSHAS组CPAP治疗后与治疗前相比DPOAE反应幅值均有提高,除500、750、1500Hz外,其余频率差异均有统计学意义(P<0.05);DPOAE检出率较治疗前提高(P<0.05),而纯音听阈、ABR反应阈与治疗前比较差异无统计学意义(P>0.05).结论 重度OSAHS患者的听功能受损,CPAP治疗可以在一定程度上改善其耳蜗功能.
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Key words
Continuous positive airway pressure (CPAP),Obstructive sleep apnea hypopnea syndrome (OSAHS),Pure tone auditory,Distorlion product otoacoustic emissions (DPOAE),Auditory brainstem re-sponse(ABR)
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