慢性间歇性低氧对颏舌肌的损伤机制
International Journal of Dermatology and Venereology（2018）
Abstract
阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea hyponea syndrome,OSAHS)是一种普遍的睡眠相关呼吸障碍疾病,主要表现为睡眠期间上呼吸道反复塌陷阻塞引起的呼吸暂停和低通气.而慢性间歇性低氧(chronic intermittent hypoxia,CIH)作为OSAHS最具代表性的病理生理特征,常引发机体低氧血症,高碳酸血症等—系列不良后果,是机体代谢性障碍及心血管疾病的潜在高危因素.研究证实上呼吸道扩张肌,尤其是颏舌肌功能异常是OSAHS的重要致病诱因,而CIH又进一步加重了颏舌肌功能损伤.本文就CIH引起颏舌肌损伤的机制做一综述.
MoreTranslated text
Key words
Sleep Apnea,Obstructive,chronic intermittent hypoxia,genioglossus
AI Read Science
Must-Reading Tree
Example
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined