辐射损伤破坏肠黏膜机械屏障机制相关研究及进展
Medical Journal of the Chinese People's Armed Police Forces（2019）
Abstract
目前,临床放射治疗给患者造成的损伤不容忽视. 放射线引起的机体损伤,特别是急性放射病,临床尚无有效预防和救治手段,其发病机制也尚不明确[1]. 肠黏膜细胞代谢速度快对放射线敏感,更容易遭受损伤. 损伤后肠黏膜屏障功能减弱甚至消失,肠道细菌及细胞分解产物进入血循环后引起的菌血症和毒血症,临床可表现为恶心、呕吐、腹泻、便血、全身炎性反应及多器官功能障碍.
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