自发性颅内出血死亡的多因素回归分析
Medical Journal of the Chinese People's Armed Police Forces(2017)
Abstract
目的 探讨自发性颅内出血(spontaneous intracerebral hemorrhage,SIH)患者30 d内死亡的危险因素.方法 回顾性分析2012-)1至2016-)1医院收治的SIH患者324例.30 d内死亡82例,为死亡组,其余242例存活患者为存活组,统计分析两组患者入院时主要临床特征.单因素和多因素logistic回归分析显示格拉斯哥昏迷评分降低、糖尿病、小脑出血、出血量增加和脑室出血等死亡的危险因素.结果 与存活组比较,死亡组年龄显著偏大[(54.38±12.47)岁vs (51.73±11.94)岁,P=0.028];高血压病显著增加(68.29% vs55.79%,P=0.047),;糖尿病显著增加(46.34% vs 27.69%,P=0.002);吸烟率显著增加(35.37%vs21.07%,P=0.009);小脑出血率显著增高(20.73% vs 8.68%,P=0.003);脑室出血率显著增高(74.39% vs 54.96%,P=0.002);手术率显著降低(20.73% vs 37.19%,P=0.006);出血量显著增多[(110.98±36.96)ml vs (77.04 ±31.81)ml,t=4.922,P=0.000];格拉斯哥昏迷评分显著降低(7.52 ±2.70 vs 9.54 ±2.06,t=4.207,P =0.000).结论 格拉斯哥昏迷评分降低、糖尿病、小脑出血、出血量增加和脑室出血是SIH患者30 d内死亡的危险因素.
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Key words
spontaneous intracranial hemorrhage,death,risk factors,multiple regression analysis
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