Duchenne型肌营养不良合并脊柱侧凸的危险因素分析

Medical Journal of the Chinese People's Armed Police Forces(2015)

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Abstract
目的:探讨 Duchenne型肌营养不良(Duchenne muscular dystrophy,DMD)合并脊柱侧凸的相关危险因素。方法选取DMD患者200例,其中并发脊柱侧凸79例为病例组,而121例未并发脊柱侧凸为对照组,采用单因素χ2检验和多因素Logistic回归分析DMD合并脊柱侧凸的相关危险因素。结果多因素分析显示下肢肌力不对称( OR=3.545,95CI:1.242~10.115)、独立行走困难(OR=16.688,95CI:5.036~55.297)、未坚持康复锻炼(OR=0.068,95CI:0.015~0.305)、跟腱挛缩形成马蹄内翻足(OR=1.597,95CI:0.462~5.524)、未使用激素治疗(OR=1.464,95CI:1.437~5.439)是DMD合并脊柱侧凸的相关危险因素。结论对有下肢肌力不对称、独立行走困难、未坚持康复锻炼、跟腱挛缩形成马蹄内翻足、未使用激素治疗等危险因素的DMD患者,应注意预防以避免发生脊柱侧凸。
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Key words
Duchenne muscular dystrophy,scoliosis,risk factors,Logistic regression
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