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脑膜瘤中ADC值、rADC值与Ki-67增殖指数的相关性分析

沈金花,董光,方龙江,王永奇,于建民,尹丹丹,张涛

Journal of Clinical Radiology（2017）

Cited 1|Views6
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Abstract
目的 探讨脑膜瘤的表观扩散系数(ADC)值、相对表观扩散系数(rADC)值与Ki-67增殖指数的相关性,提高术前评估脑膜瘤复发风险的准确率.方法 同顾性分析经病理证实且行Ki-67阳性率测定的47例脑膜瘤患者资料,术前均行常规MRI及DWI检查,测量肿瘤实质、肿瘤实质对侧镜面正常区的ADC及ADCwm值,计算rADC值(ADC/ADCwm)并分析ADC、rADC与Ki-67增殖指数的相关性.结果 脑膜瘤的ADC值与Ki-67增殖指数呈负相关(r2 =0.33,P＜0.001),rADC值与Ki-67增殖指数也呈负相关(r2 =0.31,P＜0.001).结论 ADC值、rADC值与Ki-67增殖指数的负相关关系对术前明确脑膜瘤的病理级别及手术方式的选择很有价值.
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Key words
Meningioma,Diffusion weighted imaging,Ki-67 Proliferation Index
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