益髓生血颗粒联合羟基脲治疗中间型β地中海贫血
Military Medical Journal of South China（2015）
Abstract
目的 评价中药益髓生血颗粒联合西药羟基脲治疗中间型β地中海贫血(thalassemia intermedia,TI)的临床疗效.方法 60例TI患者随机分成3组,分别口服益髓生血颗粒、口服羟基脲以及同时口服益髓生血颗粒和羟基脲3个月.治疗前后分别检测3组患者血红蛋白(hemoglobin,Hb)、胎儿血红蛋白(fetal hemoglobin,HbF)、白细胞(white blood cell,WBC),并记录不良反应.结果 57例按试验方案完成治疗和检查,联合用药组Hb和HbF升高程度优于益髓生血颗粒组和羟基脲组(P＜0.05),3组WBC改变无明显差异.结论 益髓生血颗粒联合羟基脲进一步提升Hb和HbF,使TI患者贫血症状减轻.
MoreKey words
βthalassemia intermedia,Yisui Shengxue Granule,hydroxycarbamide
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