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hCG-β反义寡脱氧核苷酸抑制正常滋养细胞hCG的分泌

陈援越,吕时铭,裘俭

JOURNAL OF RADIOMMUNOLOGY（2000）

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Abstract
目的:探讨hCG-β反义寡脱氧核苷酸(AS-0DN)是否抑制正常早期妊娠滋养细胞hCG的分泌、作用效率及对该细胞生长的影响.方法:采用放射免疫分析法检测了与hCG-β AS-ODN共培养后的正常滋养细胞hCG的含量.结果:hCG-β AS-ODN能在hCG蛋白水平产生抑制作用.结论:hCG-β AS0DN能特异地抑制正常滋养细胞hCG蛋白的分泌.
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