蒙药三味皂矾汤的抗炎作用研究

Chinese Journal of Hospital Pharmacy(2017)

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Abstract
目的:观察三味皂矾汤的抗炎作用,为该药的开发研究提供实验基础.方法:选择大鼠棉球肉芽肿、鸡蛋清致大鼠足肿胀和甲醛致大鼠足肿胀等实验模型观察三味皂矾汤的抗炎效果.结果:三味皂矾汤对大鼠棉球肉芽组织的增生有显著的抑制作用,其抑制率最高达到31.82% (P<0.01),对1~6 h内蛋清致大鼠足肿胀的抑制率最高达到31.61% (P<0.01),对1~24 h内甲醛致大鼠足肿胀的抑制率最高达到20.09% (P<0.01).结论:三味皂矾汤对亚急性吞噬细胞的浸润性炎症和对慢性增殖性组织变异性炎症均有良好的抑制作用.
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Key words
Three Soap Alum Decoction,extract,anti-inflammatory effect
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