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慢性盆腔炎灌肠液对7种致病菌体外抗菌作用的初步研究

China Pharmaceuticals(2014)

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Abstract
目的:观察慢性盆腔炎灌肠液的体外抗菌作用。方法用平皿二倍稀释法测定慢性盆腔炎灌肠液对大肠埃希菌、铜绿假单胞菌、金黄色葡萄球菌、化脓性链球菌、凝固酶阴性葡萄球菌、伤寒沙门杆菌、福氏志贺杆菌7种细菌的最小抑菌浓度( MIC)及最低杀菌浓度( MBC)。结果慢性盆腔炎灌肠液对大肠埃希菌、金黄色葡萄球菌有较明显的抑菌活性,对化脓性链球菌、伤寒沙门杆菌、福氏志贺杆菌有一定的抑菌活性,对铜绿假单胞菌、凝固酶阴性葡萄球菌的体外抑菌活性不明显。结论慢性盆腔炎灌肠液具有一定的体外抑菌活性,现时的药物浓度为最适合的药物浓度。
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Key words
chronic pelvic inflammatory disease enema,chronic pelvic inflammatory disease,in vitro antibacterial activity,two - fold agar dilution method
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