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均匀设计法优化藏药多血康提取工艺

China Pharmacy(2017)

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Abstract
目的:优化多血康的提取工艺.方法:以红景天苷、没食子酸含量及出膏率的综合评分为指标,采用U6(63)均匀设计法优化多血康提取工艺中的料液比、乙醇体积分数及提取时间,再优化提取次数,并进行验证试验.结果:最优提取工艺为采用50%乙醇,料液比1:14,浸泡1.5 h,回流提取1 h并重复2次;3次试验平均出膏率为50.18%,红景天苷和没食子酸含量分别为1.82、16.54 mg/g(RSD≤0.84%,n=3).结论:优化的多血康提取工艺合理、简单、可行.
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Key words
Tibetan medicine,Duoxuekang,Uniform design,Salidroside,Gallic acid,Content,Extraction,Technology opti-mization
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