血栓通与哌拉西林致中毒性表皮坏死松解症一例并文献复习
Practical Pharmacy and Clinical Remedies(2014)
Abstract
1例患者静脉滴注血栓通和哌拉西林1周后出现中毒性表皮坏死松解症( TEN),停药并给予甲泼尼龙、夫西地酸、丙种球蛋白及维持水电解质平衡、肠外营养等治疗,3周后皮损基本痊愈。本文通过对该病例资料进行分析,对血栓通和哌拉西林的不良反应及TEN的发病机制进行文献复习,提示临床使用这两种药物时,需要密切观察患者体温及皮肤等情况,一旦发生TEN,应立即停药,及时处理,降低病死率。
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Key words
Xueshuantong,Piperacillin,Toxic epidermal necrolysis
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